1) Automated Liquid Handler & DNA Extraction System

The system comprises equipment capable of performing the full range of processes required for biobanking, including automated identification and extraction of buffy coats from blood samples and instruments for nucleic acid extraction.

• Manufacturer: TECAN
• Model: Freedom EVO 200/150
• Specifications:
  • Freedom EVO 200 for buffycoat extraction
    1. 8 Channel Liquid Handler
    2. Robotic Arm
    3. Barcode reader for blood tube
    4. Barcode reader for storage tube
    5. Tip carrier and waste
    6. Tube carrier
    7. Microplate carrier
    8. Tube capper and decapper
    (Samplosopher cap 96s fully automatic)
  • Freedom EVO 150 for DNA extraction
    1. 8 Channel Liquid Handler
    2. Robotic Arm
    3. Microplate thermo shaker
    4. Vacuum module
    5. Magnetic plate
    6. Barcode reader for storage tube
    7. Tip carrier and waste
    8. Tube carrier

2) Next Generation Sequencing System

This system enables automated, high-throughput sequencing and analysis, supporting a broad spectrum of standard NGS applications, including targeted DNA, transcriptome, targeted RNA, and exome sequencing.

• Manufacturer: Thermofisher Scientific
• Model: Ion S5 XL System
• Specifications:

3) High-Throughput Array Plates System

This system serves as a single platform that can be applied to various genomic studies, including genotyping, gene expression analysis, splice variant analysis, and genome-wide association studies (GWAS).

• Manufacturer: Thermofisher Scientific
• Model: GeneTitan
• Specifications:
  • 1. Complete GeneTitan MC Instrument with integrated hybridization oven, fluidics processing,and imaging device
    2. Computer workstation with monitor
    3. External barcode reader
    4. Uninterruptible power supply for 220V
    5. GeneChip Command Console Software

4) High-performance Flow Cytometer

This state-of-the-art automated high-performance flow cytometer is used for phenotypic analysis of cells, enabling experiments across various fields such as immunology, cell physiology, and oncology.

• Manufacturer: Becton Dickinson
• Model: BD FACSCelesta
• Specifications:
  • 1. High-performance Flow Cytometry Sensor System Includes Laser Bench with Vis.488 / 405 / 640nm Laser and Optics with 14-Detectors System.
    2. Automated Fluidics Supply System with Workstation & FACSDiVa Software and StandardAccessories System.
    3. System Controls, Cytometer Setup and Tracking (CS&T) Beads.

5) Cell Imaging Multi-Mode Reader

The system enables observation of cell morphology under bright-field and phase-contrast modes and is equipped with fluorescence filters for DAPI, GFP, RF, and Texas Red, allowing versatile fluorescence imaging. In addition, since cell culture can be performed within the device, it is well-suited for monitoring changes in live cells.

• Manufacturer: BioTek Instruments, Inc.
• Model: Cytation 5
• Specifications:
  • 1. Image acquisition modes: Fluorescence, bright-field, phase-contrast, and color bright-field
    2. Plate reader: Fluorescence (monochromator), absorbance (monochromator), and luminescence measurement
    3. Supported plate types: 6-1536 well plate (plate reading: 6-384 well), culture dish (35mm, 60 mm), slide glass, chamber slide, T-25 flask
    4. Magnification: 4x, 10x, 20x, 40x, 60x objectives
    5. Fluorescence filters: DAPI, GFP, RFP, Texas Red
    6. Gas control: CO₂control(0-20%), O₂control(1-19%)
    7. Temperature control: up to 65°C (with anti-condensation function)
    8. Autofocus: Image-based autofocus, laser autofocus
    9. Stage control: Joystick, software control
    10. Includes Gen5 image analysis software

6) Spectral Confocal Laser Resonant Scanning Microscope

This microscope enables detailed and three-dimensional observation of tissues and intracellular structures that are difficult to visualize with conventional microscopes, providing high-resolution 3D imaging capabilities.

• Manufacturer: Olympus
• Model: FV3000RS
• Specifications:
  • 1. Laser Module – 405/488/561/640 nm Full Diode Laser
    2. Detection Module – independent 2channel Multi-Alkali PMT, 2channel GaAsP PMT,1 transmission channel (DIC)
    3. Scanning Module - (Image Resolution) : 64 x 64 to 4096 x 4096 pixels
    4. Scan Speed : 16 frames/sec at 512 x 512 with Galvo scanner.
    438 frames/sec at 512 x 32 with Resonant scanner.
    5. Motorized & Inverted Microscope IX83
    6. Software Time Lapse, 3D Imaging, Sequential Scan, FRET Analysis
    7. Digital Imaging System

7) Multiplex Analyzer

This system enables rapid and precise simultaneous analysis of various types of proteins or nucleic acids. It supports both bead-based and non-bead-based assays, offering researchers a wide range of panel options. In addition, up to 100 target analytes can be analyzed in a 96-well plate using as little as 25 µL of sample.

• Manufacturer: Luminex Corp
• Model: Luminex 200 System
• Specifications:
  • 1. xPONENT® 3.1 Software
    2. Optical system with lasers, APDs, and PMTs
    3. Flow cytometry-based system
    4. Compatible with both magnetic and non-magnetic beads
    5. Supports up to 100-plex assays
    6. Uses 96-well plates / Reads one 96-well plate in 40 minutes
    7. Enables protein and nucleic acid analysis
    8. 3.5 logs dynamic range

8) Digital PCR

Digital PCR offers approximately 1,000 times higher sensitivity than real-time PCR and provides exceptional accuracy even for low-copy samples (below 5,000 copies/μL, with single-copy resolution). In addition, it enables easy absolute quantification of samples without the need for a standard curve.

• Manufacturer : JNMedsys
• Model : Clarity dPCR
• Specifications
  • 1. Reaction volume: 15 μl/tube
    2. Operating environment: 0–70°C; 95% relative humidity, non-condensing conditions
    3. Number of partitions per reaction: 10,000
    4. Partition volume: 1.5 nl
    5. Compatible tubes: 8 strip tube
    6. For tubes: 0.2 ml
    7. Thermal cycler: Heating block compatible with 0.2 mL tubes, with adjustable ramp rate
    8. Reader throughput: 32 samples per run
    9. Number of detection channels: 2 colors (FAM and HEX/VIC)
    10. Light source: LED
    11. Detection mode: End point
    12. Reader interface: USB or Ethernet

9) Multiomics Mass Spectrometer

This high-resolution hybrid mass spectrometry system combines advanced quadrupole technology with high-performance Orbitrap technology, enabling reliable qualitative and quantitative analyses in proteomics and metabolomics.

• Manufacturer : Thermofisher Scientific
• Model : Q Exactive Plus
• Specifications
  • High-resolution mass spectrometer
    1. Hybrid quadruple-Orbitrap mass spectrometer
    2. Mass resolution: ≥280,000 (FWHM)
    3. Mass accuracy: ≤3 ppm RMS without internal calibration
    4. Sensitivity: S/N ≥100:1 @ 30 fg Buspirone on column
    5. Mass range: m/z 50–6,000
    6. Scan cycle speed: ≥12 scans per second (12 Hz) at high-resolution mode
    7. Polarity switching function: Performs one full positive and one full negative scan within 1 second during analysis
    8. Nanoelectrospray ion source: Online column heating adjustable from 30°C to 60°C
  • High-performance liquid chromatography (HPLC)
    1. Pressure range: ≥900 bar (15,000 psi)
    2. Number of solvent lines: Two or more of six lines can be selected for use
    3. Solvent degassing: Built-in type, with two or more channels
    4. Column temperature control: 5°C–120°C
    5. Autosampler injection precision: < 0.25% RSD at 1 μL, caffeine in water
  • Nano-liquid chromatography (Nano LC)
    1. Flow rate range
    -HPG nano pump: 20 nL/min–50 µL/min
    -LPG micro pump: 10–2500 μL/min
    2. Pressure range: 2–80 MPa (11,600 psi, HPG nano pump)
    3. Retention time reproducibility: ≤0.2% RSD @ 300 nL/min gradient mode
    4. Column temperature control: 5°C–110°C
    5. Autosampler sample volume: 3 x 24 deep well plates

10) Slide Scanner (Automated Tissue Scanning & Imaging System)

1. Using the automated digital fluorescence microscope, cellular and tissue responses such as cell differentiation, protein expression, and cytotoxicity can be observed. (It analyzes not only Hematoxylin & Eosin (H&E) stained samples but also samples labeled with fluorescent dyes.)

2. The imaging system consists of a high-intensity LED light source, filter cubes, optical filters, and high-quality lenses. It includes an autofocus function and allows complete control of the microscope system through software.

• Manufacturer : BioTek Instruments Inc.
• Model : LionHeartFX
• Specifications
  • 1. Imaging modes: Fluorescence, bright-field, phase-contrast, and color bright-field
    2. Light source: High power, user-replaceable LEDs or halogen
    3. Camera: 16-bit gray scale CCD camera
    4. Number of filter cubes installed: Can accommodate 4 or more
    5. Number of lenses mounted: Can accommodate 6 or more
    6. Objective lens: 4x, 10x, 20x, 40x, 60x, and 60x (oil)
    7. Image acquisition rate (single well, fastest frame rate): 2×2 binning: Up to 20 frames per second (single-color images)
    8. Resolution: 0.3 um/pixel at 20x, 0.15 um/pixel at 40x, 0.075 um/pixel at 60x
    9. Automation features: Autofocus, user-trained autofocus, auto exposure, auto-LED intensity, auto-XY stage
    10. Position control: Joy-stick or software
    11. Imaging methods: Single color, multi color, montage, time lapse, Z-stacking
    12. Image processing: Stitching, Z-projection, digital phase contrast, preprocessing, (background flatting), alignment (movie making), deconvolution

11) ELISpot Reader

The AID iSpot is one of the most successful ELISpot/FluoroSpot readers. Using the AID iSpot, both enzyme-based and fluorescence-based (FluoroSpot) ELISpot analyses can be performed.

• Manufacturer : AID (Advanced Imaging Devices GmbH)
• Model : AID Classic Reader
• Specifications
  • 1. system : close auto system
    2. enzymatic/fluorescence : minimum enzymatic
    3. Camera : CCD camera (above 2 megapixels)
    4. Illumination : LED
    ① Neon-Ring LED illumination system
    Xenon Lamp (fluorescence)
    ② top light : 120 LED ring
    bottom light : High illumination, uniform flat light pannel
    5. Scanning stage
    ① Quad Pack control system
    ② 4 step image step mode
    6. Plate type : 96well plate
    7. Quality control : software QC mode
    8. Validation : GLP

12) Real-Time Nucleic Acid Quantification System (qPCR)

This instrument utilizes fluorescent labels, including the 5’ nuclease assay (TaqMan probe) and double-stranded DNA binding dye (SYBR Green I), to measure the quantity of target DNA or RNA in a sample in real time. It can be applied to a variety of analyses, such as quantification and detection of specific genes, mRNA expression levels, and comparison of relative gene expression between different groups.

• Manufacturer : Thermo Scientific
• Model : Applied Biosystems Step One Plus Real-Time PCR System
• Specifications
  • 1. Reaction well: 96 wells
    2. Maximum ramp rate: 4.6°C/sec or higher
    3. Heating and cooling rate: Fast mode: 2.2℃/sec or higher
    4. Sample detection: LED
    5. Detection channels: 4 filters or more
    6. Dynamic range: 9 logs or greater
    7. Block mode: 96-well standard

13) Cell Separator

The AutoMACS Pro is an instrument that rapidly isolates target cells using very small magnetic microbeads conjugated with antibodies specific to target antigens and electromagnetic separation technology

• Manufacturer : Miltenyi Biotec.
• Model : AutoMACS pro
• Specifications
  • 1. Fully automated cell separation
    ① Enables continuous automatic separation of up to 5 samples
    ② Automated system minimizes hands-on time
    2. Uses standardized protocols
    ① Pre-installed programs
    ② Provides reproducible results
    ③ Program selection available based on target cell frequency and antigen expression level
    3. Ultrafast cell separation
    Processes up to 4 × 10⁹ total cells in 5 minutes using the standard program
    4. Uses reusable dedicated columns
    ① Each column can be used for up to 100 tests

14) Real Time PCR System

This instrument utilizes fluorescent labels, including the 5’ nuclease assay (TaqMan probe) and double-stranded DNA binding dye (SYBR Green I), to measure the quantity of target DNA or RNA in a sample in real time. It can be applied to a variety of analyses, such as quantification and detection of specific genes, mRNA expression levels, and comparison of relative gene expression between different groups.

• Manufacturer : Roche Diagnostics
• Model : LightCycler®96 Instrument
• Specifications
  • 1. Reaction well: 96-well or equivalent/higher
    2. Maximum ramp rate: 4.4°C/sec or equivalent/higher
    3. Consumable type: Plate or equivalent/higher
    4. Sample detection: LED or Xenon lamp
    5. Detection channels: 4 filters or equivalent/higher
    6. Block mode: 96-well standard
    7. Passive reference dye
    8. Standalone operation (does not require additional equipment such as a desktop or laptop computer)

15) Microplate Reader

This instrument is an RT-QuIC assay (Real-Time Quaking-Induced Conversion) analyzer used to detect the abnormal accumulation of alpha-synuclein—a protein associated with Parkinson’s disease—in the cerebrospinal fluid of patients with neurodegenerative disorders. Fluorescently labeled samples contained in plate wells can be measured using a filter-based method to accurately detect their specific emission wavelengths.

• Manufacturer : BMG LABTECH
• Model : FLUOstar Omega
• Specifications
  • 1. Supports fluorescence (FL, FRET), time-resolved fluorescence (TRF, TR-FRET), and luminescence (LUM, BRET) measurements
    2. Supported plate types: Compatible with plates from 6-well to 384-well formats
    3. Uses filters optimized for the fluorescence wavelength to ensure accurate measurements (up to 8 excitation and 8 emission filters can be installed).
    -Measurable wavelength range: 240–740 nm
    4. Sensitivity
    1) Fluorescence: FI < 0.2 fmol/well fluorescein
    2) Luminescence: LUM 20 amol/well ATP DLReadyTM
    3) Time-resolved fluorescence (TRF): TRF < 30 amol/well europiumHigh-end TRF for Omega < 3 amol/well europium
    5. Capable of both time-course and end-point measurements
    6. Includes analysis software (facilitating the calculation of results such as linear regression, 4- and 5-parameter logistic curves, hyperbola, segmental regression, cubic spline, 2nd- and 3rd-order polynomial fitting, EC50, IC50, and r2 values)
    7. Xenon flash lamp
    8. Temperature control range: +4°C above ambient up to 65°C

16) Library Quality Assessment Device (Automated Electrophoresis System)

This automated instrument enables broad-spectrum analysis of nucleic acids (DNA and RNA) while minimizing manual handling. It uses pre-formulated reagent kits to provide highly reproducible and standardized results accessible to all users.

• Manufacturer : Agilent
• Model : 4200 TapeStation system
• Specifications
  • 1. Sample throughput: 96 samples per run (90 minutes)
    2. Minimum sample volume
    ① DNA: 2 ㎕
    ② RNA: 6 ㎕
    3. Sample integrity analysis metrics
    ① DNA: Provides integrity metrics such as the DNA Integrity Number (DIN) and Genomic DNA Quality Score (GQS) to assess DNA degradation levels
    ② RNA: Provides integrity metrics such as the RNA Integrity Number (RIN) and RNA Quality Score (RQS) to assess RNA degradation levels
    4. DNA ScreenTape or chip kit types:
    ① DNA 1000 base pair analysis kit: 35–1,000 bp
    ② DNA 5000 base pair analysis kit: 1,000–5,000 bp
    ③ High Sensitivity DNA analysis kit: 100–5,000 bp
    ④ Genomic DNA analysis kit: 200–40,000 bp
    5. RNA ScreenTape or chip kit types:
    ① RNA 5000 nucleotide analysis kit: 100–6,000 nt
    6. Barcode reader (plate) enhances sample management efficiency by recognizing barcodes at the plate level.
    7. Application of RFTaq technology enables convenient management of consumable replacement cycles, allowing users to monitor usage and replacement schedules through the software.
    8. The detector ensures high reproducibility without wavelength interference within the PCR dye detection range.
    9. Equipped with a temperature control system that maintains consistent performance regardless of external temperature changes, ensuring high reproducibility.

17) High-Throughput Automated Electrophoresis System (Automated Electrophoresis System)

This fully automated electrophoresis system uses ready-to-run kits to separate DNA and RNA based on molecular weight. It can analyze the ratio, concentration, and purity of RNA fragments such as total RNA, mRNA, and miRNA, as well as perform qualitative analysis of cRNA/cDNA or size-fractionated RNA/DNA. The system is applicable to various experimental methods, including genetic profile screening, RFLP, AFLP, gene expression analysis, and viral/bacterial DNA testing.

• Manufacturer : QIAGEN
• Model : QIAxcel Advanced System
• Specifications
  • 1. Sample throughput: 1–96 samples or more
    2. Analytical sensitivity: 0.1 ng/㎕ or higher
    3. Resolution: < 3–7 bp or better
    4. Minimum sample volume required: 1 ㎕ or more
    5. Sample consumption per analysis: 0.1 ㎕ or more
    6. Number of channels for simultaneous analysis: 12 channels or more
    7. Detection range: 15 bp–10 kb or higher, 100–6,000 nt or higher for RNA
    8. Analysis time (for 12 samples): 3–10 minutes or more
    9. Light source: Light-emitting diodes (LEDs) or laser